Acanthosis nigricans
☆ Di encamên 2022-an de Stiftung Warentest ji Almanyayê, razîbûna xerîdar bi ModelDerm tenê ji şêwirmendên telemedicine drav hindik hindiktir bû.
Di mirovên qelew de gelemperî ye.
References
Acanthosis nigricans diyardeyek çermî ya rewşek bingehîn e. Ew bi gelemperî di pelikên çermê yên mîna stû, mil û gewr de xuya dike, mîna lekeyên tarî yên qedifî yên bi rehên nezelal xuya dikin. Ev rewş bi gelemperî bi şekir û berxwedana însulînê ve girêdayî ye, lê di rewşên kêm de, ew dikare kansera hundurê laş nîşan bide. Di heman demê de dibe ku ew ji ber pirsgirêkên hormonê an ji girtina dermanên taybetî yên wekî steroîd û hebên kontrolkirina zayînê jî xuya bibe.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans (AN) rewşek çermê hevpar e ku bi pirsgirêkên tenduristiyê yên cihêreng ên mîna berxwedana însulînê, şekir, qelewbûn, hin penceşêrê, pirsgirêkên hormonal, û reaksiyonên li ser dermanan ve girêdayî ye. Dermankirina AN li ser çareserkirina pirsgirêkên tenduristiyê yên bingehîn disekine. Di destpêkê de, bijîjk ji bo nîşanên sendroma berxwedana însulînê, ku tê de qelewbûn, kolesterolê bilind, tansiyona xwînê ya bilind, û şekirê şekir 2 hene, kontrol dikin. Bijîjk bi gelemperî topical retinoids wekî bijareya dermankirinê ya yekem destnîşan dikin, ku dikare di stûrbûna çerm de bibe alîkar. Lêbelê, ew dikarin bi tevahî tarîbûna çerm çareser nekin. Vebijarkên din ên dermankirinê (salicylic acid, podophyllin, urea, calcipotriol) jî hewceyê serîlêdana pir caran hewce ne.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
○ Causes
Ew bi gelemperî di mirovên ji 40 salî piçûktir de çêdibe, dibe ku ji hêla genetîkî ve were mîras kirin û bi qelewbûn an endokrînopatiyên mîna hîpotyroidîzm, akromegalî, nexweşiya hêkdankên polycystic, şekirê însulîn-berxwedêr an nexweşiya Cushing ve girêdayî ye.
○ Dermankirin - Dermanên OTC
#40% urea cream